Unified power quality conditioner (UPQC) holds the capability of solving power quality problems, especially shows good performance in the voltage sag compensation. In this paper, a compensation strategy based on simultaneous reactive power injection for UPQC (namely UPQC-SRI) is proposed to address the issue of voltage sag. The proposed UPQC-SRI determines the injection angle of compensation voltage with consideration of optimal configuration of UPQC current-carrying. Moreover, the compensation strategy also considers the current-carrying limit of UPQC, and then the zero active power injection region of UPQC-SRI (also called UPQC-SRI region) is obtained. Under the conditions which exceed the UPQC-SRI region, the limit value of shunt current is determined by this proposed strategy. Finally, the proposed strategy and the corresponding algorithm are verified under the PSCAD/EMTDC platform. The result indicates the proposed UPQC-SRI strategy in this paper can provide more persistent voltage sag compensation than the previous strategies for the sensitive load.