Along with the improvement of electrical equipment reliability, people’s unsafe behaviors and human errors have become one of main sources of risks in power systems. However, there is no comprehensive study on human factors and human reliability analysis in power systems. In allusion to this situation, this paper attempts to analyze the impact of human factors on power system reliability. First, this paper introduces current situation of human factors in power systems and the latest research progress in this field. Several analysis methods are proposed according to specified situations, and these methods are verified by some power system practical cases. On this base, this paper illustrates how human factors affect power system operation reliability from 2 typical aspects: imperfect maintenance caused by human errors, and impact of human factors on emergency dispatch operation and power system cascading failure. Finally, based on information decision and action in crew (IDAC), a novel dispatcher training evaluation simulation system (DTESS) is established, which can incorporate all influencing factors. Once fully developed, DTESS can be used to simulate dispatchers’ response when encountering an initial event, and improve power system dispatching reliability.